Drug interactions
Arformoterol + Efavirenz
Severity: Moderate
Arformoterol and Efavirenz: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Efavirenz can prolong QT and arformoterol, a long-acting beta-agonist, may cause hypokalemia and QT effects. Risk is modest at standard doses but greater with other QT risks.
What this interaction means in plain words
Arformoterol and Efavirenz can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Efavirenz belongs to Anti Virals.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia.
What to do
Monitor ECG and serum potassium in patients with cardiac disease or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Efavirenz
- Cobimetinib + Efavirenz Contraindicated
- Dienogest / estradiol valerate + Efavirenz Contraindicated
- Dihydroergotamine intranasal + Efavirenz Contraindicated
- Dihydroergotamine + Efavirenz Contraindicated
- Doravirine + Efavirenz Contraindicated
- Efavirenz + Elbasvir / grazoprevir Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Efavirenz?
MediHelp rates the interaction as moderate. Arformoterol and Efavirenz can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Efavirenz can prolong QT and arformoterol, a long-acting beta-agonist, may cause hypokalemia and QT effects. Risk is modest at standard doses but greater with other QT risks.
How serious is the interaction between Arformoterol and Efavirenz?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac disease or other QT-prolonging drugs.
What other medicines interact with Efavirenz?
MediHelp also lists interactions of Efavirenz with, for example, Cobimetinib, Dienogest / estradiol valerate, Dihydroergotamine intranasal. The full list is on the Efavirenz page.
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