Drug interactions
Arformoterol + Eprosartan-hydrochlorothiazide
Severity: Moderate
Arformoterol and Eprosartan-hydrochlorothiazide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol, a long-acting beta-2 agonist, and hydrochlorothiazide can each lower serum potassium. Together they may cause hypokalemia and, in susceptible patients, ECG changes or arrhythmias.
What this interaction means in plain words
Arformoterol and Eprosartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Eprosartan-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Additive hypokalemia from renal potassium loss caused by the thiazide and intracellular potassium shift caused by the beta-2 agonist.
What to do
Check serum potassium periodically and correct deficits. Take extra care in patients with cardiac disease, hypoxia or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Eprosartan-hydrochlorothiazide?
MediHelp rates the interaction as moderate. Arformoterol and Eprosartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol, a long-acting beta-2 agonist, and hydrochlorothiazide can each lower serum potassium. Together they may cause hypokalemia and, in susceptible patients, ECG changes or arrhythmias.
How serious is the interaction between Arformoterol and Eprosartan-hydrochlorothiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium periodically and correct deficits. Take extra care in patients with cardiac disease, hypoxia or other QT-prolonging drugs.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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