Drug interactions
Arformoterol + Nadolol
Severity: Major
Arformoterol and Nadolol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nadolol blocks beta-2 receptors and can antagonize the bronchodilator effect of arformoterol. This may cause loss of asthma or COPD control and bronchospasm.
What this interaction means in plain words
Arformoterol and Nadolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Nadolol belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism at beta-2 adrenergic receptors.
What to do
Avoid the combination where possible; if a beta-blocker is required, prefer a cardioselective agent and monitor lung function and symptoms.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Atenolol-chlorthalidone + Nadolol Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Nadolol?
MediHelp rates the interaction as major. Arformoterol and Nadolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Nadolol blocks beta-2 receptors and can antagonize the bronchodilator effect of arformoterol. This may cause loss of asthma or COPD control and bronchospasm.
How serious is the interaction between Arformoterol and Nadolol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if a beta-blocker is required, prefer a cardioselective agent and monitor lung function and symptoms.
What other medicines interact with Nadolol?
MediHelp also lists interactions of Nadolol with, for example, Acebutolol, Adrenaline-articaine, Albuterol. The full list is on the Nadolol page.
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