Drug interactions
Arformoterol + Ofloxacin
Severity: Moderate
Arformoterol and Ofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol, a long-acting beta2 agonist, can cause hypokalemia, tachycardia and QT prolongation. Ofloxacin may add a small QT effect, increasing arrhythmia risk in susceptible patients.
What this interaction means in plain words
Arformoterol and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Ofloxacin belongs to Anti Bacterial.
Why it happens
Additive effects on cardiac repolarization with beta2-agonist-induced hypokalemia.
What to do
Check potassium and magnesium in at-risk patients and correct deficits. Monitor the ECG in patients with cardiac disease or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Ofloxacin?
MediHelp rates the interaction as moderate. Arformoterol and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol, a long-acting beta2 agonist, can cause hypokalemia, tachycardia and QT prolongation. Ofloxacin may add a small QT effect, increasing arrhythmia risk in susceptible patients.
How serious is the interaction between Arformoterol and Ofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium in at-risk patients and correct deficits. Monitor the ECG in patients with cardiac disease or other QT-prolonging drugs.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
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