Drug interactions
Arformoterol + Quinine
Severity: Moderate
Arformoterol and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol, a long-acting beta-agonist, may cause tachycardia, hypokalemia and QTc prolongation. Combined with quinine, this may increase arrhythmia risk, especially in patients with heart disease.
What this interaction means in plain words
Arformoterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Quinine belongs to Anti Parasitic.
Why it happens
Additive QT prolongation, with beta-agonist induced hypokalemia.
What to do
Monitor ECG and serum potassium in patients with cardiac risk factors. Avoid exceeding labeled arformoterol doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Quinine?
MediHelp rates the interaction as moderate. Arformoterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol, a long-acting beta-agonist, may cause tachycardia, hypokalemia and QTc prolongation. Combined with quinine, this may increase arrhythmia risk, especially in patients with heart disease.
How serious is the interaction between Arformoterol and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac risk factors. Avoid exceeding labeled arformoterol doses.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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