Drug interactions
Aspirin + Mistletoe
Severity: Minor
Aspirin and Mistletoe: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aspirin inhibits platelet function and can raise bleeding risk, while mistletoe has been proposed to have effects on coagulation in the opposite direction. The net effect on hemostasis is unpredictable and not well documented.
What this interaction means in plain words
Aspirin and Mistletoe have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing pharmacodynamic effects on hemostasis are theorized; the mechanism is not established.
What to do
Ask patients about mistletoe use and watch for unusual bruising or bleeding in those on regular aspirin. No dose change is needed unless bleeding occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mistletoe
Frequently asked questions
Can I take Aspirin with Mistletoe?
MediHelp rates the interaction as minor. Aspirin and Mistletoe have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aspirin inhibits platelet function and can raise bleeding risk, while mistletoe has been proposed to have effects on coagulation in the opposite direction. The net effect on hemostasis is unpredictable and not well documented.
How serious is the interaction between Aspirin and Mistletoe?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about mistletoe use and watch for unusual bruising or bleeding in those on regular aspirin. No dose change is needed unless bleeding occurs.
What other medicines interact with Mistletoe?
MediHelp also lists interactions of Mistletoe with, for example, Aceclofenac, Aescin, Aspirin / citric acid / sodium bicarbonate. The full list is on the Mistletoe page.
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