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Drug interactions

Aspirin rectal + Mistletoe

Severity: Minor

Aspirin rectal and Mistletoe: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Rectal aspirin is absorbed systemically and inhibits platelets, which may increase bleeding tendency. Mistletoe is thought to have opposing effects on coagulation, so the net result is uncertain.

What this interaction means in plain words

Aspirin rectal and Mistletoe have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Opposing pharmacodynamic effects on hemostasis are theorized; the mechanism is not established.

What to do

Ask about herbal use and monitor for bleeding or bruising in regular aspirin users. Stop mistletoe if bleeding problems appear.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Aspirin rectal with Mistletoe?

MediHelp rates the interaction as minor. Aspirin rectal and Mistletoe have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rectal aspirin is absorbed systemically and inhibits platelets, which may increase bleeding tendency. Mistletoe is thought to have opposing effects on coagulation, so the net result is uncertain.

How serious is the interaction between Aspirin rectal and Mistletoe?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use and monitor for bleeding or bruising in regular aspirin users. Stop mistletoe if bleeding problems appear.

What other medicines interact with Mistletoe?

MediHelp also lists interactions of Mistletoe with, for example, Aceclofenac, Aescin, Aspirin / citric acid / sodium bicarbonate. The full list is on the Mistletoe page.

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