Drug interactions
Acetylsalicylic acid + Verapamil
Severity: Minor
Acetylsalicylic acid and Verapamil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Verapamil has mild antiplatelet activity and may add to the effect of aspirin, slightly raising bleeding tendency. Clinical consequences are usually small.
What this interaction means in plain words
Acetylsalicylic acid and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Acetylsalicylic acid belongs to Musculoskeletal; Verapamil belongs to Cardiovascular.
Why it happens
Additive platelet inhibition through reduced platelet calcium influx plus cyclooxygenase inhibition.
What to do
No dose adjustment is required. Watch for bruising or bleeding, especially with other antithrombotics.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac intranasal Contraindicated
- Abciximab + Acetylsalicylic acid Major
- Acemetacin + Acetylsalicylic acid Major
- Acetazolamide + Acetylsalicylic acid Major
- Acetylsalicylic acid + Alteplase Major
Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Frequently asked questions
Can I take Acetylsalicylic acid with Verapamil?
MediHelp rates the interaction as minor. Acetylsalicylic acid and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Verapamil has mild antiplatelet activity and may add to the effect of aspirin, slightly raising bleeding tendency. Clinical consequences are usually small.
How serious is the interaction between Acetylsalicylic acid and Verapamil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required. Watch for bruising or bleeding, especially with other antithrombotics.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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