Drug interactions
Aspirin rectal + Bimatoprost
Severity: Minor
Aspirin rectal and Bimatoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prostaglandin analogues lower intraocular pressure partly through uveoscleral outflow, and NSAIDs inhibit prostaglandin synthesis, so they might blunt the pressure-lowering effect. Reports are conflicting and the clinical effect is generally small.
What this interaction means in plain words
Aspirin rectal and Bimatoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Cyclooxygenase inhibition may counteract prostaglandin-mediated outflow; the effect is not well established.
What to do
No change is usually needed; check intraocular pressure at routine follow-up if control worsens after starting regular NSAID use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bimatoprost
- Bimatoprost + Latanoprost Moderate
- Bimatoprost + Latanoprostene bunod Moderate
- Bimatoprost + Tafluprost Moderate
- Bimatoprost + Travoprost Moderate
- Aspirin + Bimatoprost Minor
- Bimatoprost + Bromfenac Minor
Frequently asked questions
Can I take Aspirin rectal with Bimatoprost?
MediHelp rates the interaction as minor. Aspirin rectal and Bimatoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Prostaglandin analogues lower intraocular pressure partly through uveoscleral outflow, and NSAIDs inhibit prostaglandin synthesis, so they might blunt the pressure-lowering effect. Reports are conflicting and the clinical effect is generally small.
How serious is the interaction between Aspirin rectal and Bimatoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is usually needed; check intraocular pressure at routine follow-up if control worsens after starting regular NSAID use.
What other medicines interact with Bimatoprost?
MediHelp also lists interactions of Bimatoprost with, for example, Latanoprost, Latanoprostene bunod, Tafluprost. The full list is on the Bimatoprost page.
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