Drug interactions
Bimatoprost + Latanoprost
Severity: Moderate
Bimatoprost and Latanoprost: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Using two prostaglandin analogue eye drops together may lessen the pressure-lowering effect and in some cases raise intraocular pressure. There is no benefit from combining them.
What this interaction means in plain words
Bimatoprost and Latanoprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bimatoprost belongs to Miscellaneous; Latanoprost belongs to Miscellaneous.
Why it happens
Mechanism is not established; competing prostaglandin receptor effects have been proposed.
What to do
Use only one prostaglandin analogue at a time. If more pressure lowering is needed, add a drug from another class such as a beta-blocker or carbonic anhydrase inhibitor.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bimatoprost
- Bimatoprost + Latanoprostene bunod Moderate
- Bimatoprost + Tafluprost Moderate
- Bimatoprost + Travoprost Moderate
- Aspirin rectal + Bimatoprost Minor
- Aspirin + Bimatoprost Minor
- Bimatoprost + Bromfenac Minor
Other interactions of Latanoprost
- Latanoprost + Latanoprostene bunod Moderate
- Latanoprost + Tafluprost Moderate
- Latanoprost + Travoprost Moderate
- Aspirin rectal + Latanoprost Minor
- Aspirin + Latanoprost Minor
- Bromfenac + Latanoprost Minor
Frequently asked questions
Can I take Bimatoprost with Latanoprost?
MediHelp rates the interaction as moderate. Bimatoprost and Latanoprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Using two prostaglandin analogue eye drops together may lessen the pressure-lowering effect and in some cases raise intraocular pressure. There is no benefit from combining them.
How serious is the interaction between Bimatoprost and Latanoprost?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only one prostaglandin analogue at a time. If more pressure lowering is needed, add a drug from another class such as a beta-blocker or carbonic anhydrase inhibitor.
What other medicines interact with Bimatoprost?
MediHelp also lists interactions of Bimatoprost with, for example, Latanoprostene bunod, Tafluprost, Travoprost. The full list is on the Bimatoprost page.
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