Drug interactions
Aspirin rectal + Timolol
Severity: Minor
Aspirin rectal and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Regular use of higher-dose aspirin may reduce the antihypertensive effect of timolol. The effect is small at low doses.
What this interaction means in plain words
Aspirin rectal and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of prostaglandin synthesis by aspirin leads to sodium and fluid retention that opposes beta-blocker effects.
What to do
Monitor blood pressure if analgesic-dose aspirin is used regularly. No action is needed for occasional or low-dose use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Frequently asked questions
Can I take Aspirin rectal with Timolol?
MediHelp rates the interaction as minor. Aspirin rectal and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Regular use of higher-dose aspirin may reduce the antihypertensive effect of timolol. The effect is small at low doses.
How serious is the interaction between Aspirin rectal and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if analgesic-dose aspirin is used regularly. No action is needed for occasional or low-dose use.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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