Drug interactions
Atenolol + Candesartan
Severity: Moderate
Atenolol and Candesartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The two drugs together lower blood pressure additively and are often combined deliberately. Candesartan can raise potassium, and beta-blockers may modestly contribute, while candesartan is contraindicated in pregnancy regardless of atenolol.
What this interaction means in plain words
Atenolol and Candesartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Candesartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effect; angiotensin receptor blockade reduces aldosterone, and beta-blockade reduces cellular potassium uptake.
What to do
Monitor blood pressure, serum potassium and renal function after initiation or dose changes, especially in renal impairment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Other interactions of Candesartan
- Aliskiren + Candesartan Contraindicated
- Candesartan + Sparsentan Contraindicated
- Amifostine + Candesartan Major
- Amiloride + Candesartan Major
- Amlodipine-benazepril + Candesartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Candesartan Major
Frequently asked questions
Can I take Atenolol with Candesartan?
MediHelp rates the interaction as moderate. Atenolol and Candesartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The two drugs together lower blood pressure additively and are often combined deliberately. Candesartan can raise potassium, and beta-blockers may modestly contribute, while candesartan is contraindicated in pregnancy regardless of atenolol.
How serious is the interaction between Atenolol and Candesartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum potassium and renal function after initiation or dose changes, especially in renal impairment.
What other medicines interact with Atenolol?
MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.
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