Drug interactions
Atenolol + Terazosin
Severity: Moderate
Atenolol and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Terazosin and atenolol together lower blood pressure more than either alone. Postural hypotension and first-dose syncope from terazosin may be more pronounced.
What this interaction means in plain words
Atenolol and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Terazosin belongs to Genitourinary.
Why it happens
Additive hypotension from alpha-1 adrenergic blockade and beta-1 blockade.
What to do
Start terazosin at a low bedtime dose and titrate gradually. Monitor orthostatic blood pressure and heart rate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Terazosin?
MediHelp rates the interaction as moderate. Atenolol and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Terazosin and atenolol together lower blood pressure more than either alone. Postural hypotension and first-dose syncope from terazosin may be more pronounced.
How serious is the interaction between Atenolol and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start terazosin at a low bedtime dose and titrate gradually. Monitor orthostatic blood pressure and heart rate.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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