Drug interactions
Atomoxetine + Degarelix
Severity: Moderate
Atomoxetine and Degarelix: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen deprivation therapy with degarelix can prolong the QT interval, and atomoxetine may add modest QT and heart rate effects. The combined risk is usually small but matters in patients with cardiac disease.
What this interaction means in plain words
Atomoxetine and Degarelix can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Degarelix belongs to Endocrine.
Why it happens
Additive QT prolongation (pharmacodynamic).
What to do
Review baseline ECG and electrolytes, and monitor ECG in patients with cardiac risk factors. Consider an alternative ADHD treatment if QT lengthening develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Other interactions of Degarelix
- Degarelix + Pimozide Contraindicated
- Degarelix + Thioridazine Contraindicated
- Amiodarone + Degarelix Major
- Amisulpride + Degarelix Major
- Anagrelide + Degarelix Major
- Cisapride + Degarelix Major
Frequently asked questions
Can I take Atomoxetine with Degarelix?
MediHelp rates the interaction as moderate. Atomoxetine and Degarelix can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgen deprivation therapy with degarelix can prolong the QT interval, and atomoxetine may add modest QT and heart rate effects. The combined risk is usually small but matters in patients with cardiac disease.
How serious is the interaction between Atomoxetine and Degarelix?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review baseline ECG and electrolytes, and monitor ECG in patients with cardiac risk factors. Consider an alternative ADHD treatment if QT lengthening develops.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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