Drug interactions
Atomoxetine + Dobutamine
Severity: Moderate
Atomoxetine and Dobutamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atomoxetine can raise blood pressure and heart rate through noradrenergic reuptake inhibition, and dobutamine has inotropic and chronotropic effects. Together they may cause excessive tachycardia or hypertension.
What this interaction means in plain words
Atomoxetine and Dobutamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Dobutamine belongs to Cardiovascular.
Why it happens
Additive sympathomimetic cardiovascular effects.
What to do
Monitor blood pressure, heart rate and rhythm during dobutamine infusion and titrate the dose to the lowest effective rate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dobutamine
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Dobutamine?
MediHelp rates the interaction as moderate. Atomoxetine and Dobutamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atomoxetine can raise blood pressure and heart rate through noradrenergic reuptake inhibition, and dobutamine has inotropic and chronotropic effects. Together they may cause excessive tachycardia or hypertension.
How serious is the interaction between Atomoxetine and Dobutamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and rhythm during dobutamine infusion and titrate the dose to the lowest effective rate.
What other medicines interact with Dobutamine?
MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.
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