Drug interactions
Atomoxetine + Fingolimod
Severity: Moderate
Atomoxetine and Fingolimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fingolimod causes bradycardia on initiation and has been linked to QT effects, and atomoxetine may add QT and heart rate changes. Combined use may increase arrhythmia risk in vulnerable patients.
What this interaction means in plain words
Atomoxetine and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Fingolimod belongs to Central Nervous System.
Why it happens
Additive effects on cardiac conduction and QT interval (pharmacodynamic).
What to do
Perform ECG and first-dose monitoring as per fingolimod labeling, and monitor heart rate and QT in patients on atomoxetine. Correct electrolyte abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Atomoxetine and Fingolimod, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Atomoxetine with Fingolimod?
MediHelp rates the interaction as moderate. Atomoxetine and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fingolimod causes bradycardia on initiation and has been linked to QT effects, and atomoxetine may add QT and heart rate changes. Combined use may increase arrhythmia risk in vulnerable patients.
How serious is the interaction between Atomoxetine and Fingolimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform ECG and first-dose monitoring as per fingolimod labeling, and monitor heart rate and QT in patients on atomoxetine. Correct electrolyte abnormalities.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
