Drug reference
fingolimod
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (MS Drugs)
Mechanism of action
to the active metabolite, fingolimod-phosphate. Binds with high affinity to sphingosine 1-phosphate receptors 1, 3, 4, and 5; blocks lymphocyte capacity to egress from lymph nodes, and thereby reduces the lymphocyte count in peripheral blood
Common side effects
- Headache
- Nausea
- Liver transaminase elevations (ALT/GGT/AST)
- Sinusitis
- Influenza viral infection
- Abdominal pain
Known interactions (7)
- fingolimod + pimozide Contraindicated
- fingolimod + quinidine Contraindicated
- fingolimod + sotalol Contraindicated
- fingolimod + thioridazine Contraindicated
- amiodarone + fingolimod Major
- dronedarone + fingolimod Major
- fingolimod + upadacitinib Major
Related conditions
Frequently asked questions
What drug class is fingolimod?
fingolimod belongs to: Central Nervous System.
How does fingolimod work?
to the active metabolite, fingolimod-phosphate. Binds with high affinity to sphingosine 1-phosphate receptors 1, 3, 4, and 5; blocks lymphocyte capacity to egress from lymph nodes, and thereby reduces the lymphocyte count in peripheral blood
What are the common side effects of fingolimod?
Headache, Nausea, Liver transaminase elevations (ALT/GGT/AST), Sinusitis, Influenza viral infection, Abdominal pain
Which drugs interact with fingolimod?
pimozide, quinidine, sotalol, thioridazine, amiodarone, dronedarone, upadacitinib
Full monographs, dosing and an interaction checker in the MediHelp app
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