Drug interactions
Atorvastatin + Bazedoxifene / conjugated estrogens
Severity: Minor
Atorvastatin and Bazedoxifene / conjugated estrogens: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin may modestly increase exposure to P-gp substrates such as bazedoxifene, though clinical significance is small.
What this interaction means in plain words
Atorvastatin and Bazedoxifene / conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Atorvastatin weakly inhibits intestinal P-glycoprotein efflux.
What to do
No dose change is required; monitor for estrogen-related adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Bazedoxifene / conjugated estrogens?
MediHelp rates the interaction as minor. Atorvastatin and Bazedoxifene / conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin may modestly increase exposure to P-gp substrates such as bazedoxifene, though clinical significance is small.
How serious is the interaction between Atorvastatin and Bazedoxifene / conjugated estrogens?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is required; monitor for estrogen-related adverse effects.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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