Drug interactions
Atorvastatin + Ethinyl estradiol-levonorgestrel
Severity: Minor
Atorvastatin and Ethinyl estradiol-levonorgestrel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin has been reported to modestly raise ethinyl estradiol exposure, possibly through effects on intestinal metabolism or transport. The change is small and rarely clinically meaningful.
What this interaction means in plain words
Atorvastatin and Ethinyl estradiol-levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atorvastatin belongs to Cardiovascular; Ethinyl estradiol-levonorgestrel belongs to Endocrine.
Why it happens
Possible inhibition of intestinal sulfation or transport of ethinyl estradiol; not fully established.
What to do
No dose adjustment is needed; be aware of possible estrogenic effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ethinyl estradiol-levonorgestrel
- Ethinyl estradiol-levonorgestrel + Fezolinetant Contraindicated
- Ethinyl estradiol-levonorgestrel + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Ethinyl estradiol-levonorgestrel + Tranexamic acid Contraindicated
- Aminocaproic acid + Ethinyl estradiol-levonorgestrel Major
- Amobarbital + Ethinyl estradiol-levonorgestrel Major
- Anastrozole + Ethinyl estradiol-levonorgestrel Major
Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Ethinyl estradiol-levonorgestrel?
MediHelp rates the interaction as minor. Atorvastatin and Ethinyl estradiol-levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin has been reported to modestly raise ethinyl estradiol exposure, possibly through effects on intestinal metabolism or transport. The change is small and rarely clinically meaningful.
How serious is the interaction between Atorvastatin and Ethinyl estradiol-levonorgestrel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; be aware of possible estrogenic effects.
What other medicines interact with Ethinyl estradiol-levonorgestrel?
MediHelp also lists interactions of Ethinyl estradiol-levonorgestrel with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-levonorgestrel page.
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