Drug interactions
Atorvastatin + Ethinylestradiol
Severity: Minor
Atorvastatin and Ethinylestradiol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin has been reported to modestly increase ethinylestradiol exposure in oral contraceptive studies. The effect is small and rarely clinically significant.
What this interaction means in plain words
Atorvastatin and Ethinylestradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible reduced first-pass metabolism or efflux of ethinylestradiol; mechanism not firmly established.
What to do
No dose adjustment is usually required; be aware of estrogenic adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Ethinylestradiol?
MediHelp rates the interaction as minor. Atorvastatin and Ethinylestradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin has been reported to modestly increase ethinylestradiol exposure in oral contraceptive studies. The effect is small and rarely clinically significant.
How serious is the interaction between Atorvastatin and Ethinylestradiol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually required; be aware of estrogenic adverse effects.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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