Drug interactions
Atorvastatin + Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate
Severity: Minor
Atorvastatin and Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin modestly increases ethinylestradiol exposure, roughly by a fifth to a quarter. This is rarely clinically important but may slightly increase estrogenic effects.
What this interaction means in plain words
Atorvastatin and Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Atorvastatin may reduce first-pass metabolism or sulfation of ethinylestradiol; the exact mechanism is not firmly established.
What to do
No dose change is usually needed. Be aware of estrogenic adverse effects such as breast tenderness or nausea.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate?
MediHelp rates the interaction as minor. Atorvastatin and Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin modestly increases ethinylestradiol exposure, roughly by a fifth to a quarter. This is rarely clinically important but may slightly increase estrogenic effects.
How serious is the interaction between Atorvastatin and Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed. Be aware of estrogenic adverse effects such as breast tenderness or nausea.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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