Drug interactions
Atorvastatin + Quercetin
Severity: Minor
Atorvastatin and Quercetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quercetin affects P-glycoprotein and CYP enzymes in vitro, but the effect on atorvastatin in humans is unclear. Any change in exposure is probably small.
What this interaction means in plain words
Atorvastatin and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Quercetin may modulate P-glycoprotein and CYP3A4; the net effect on atorvastatin is not established.
What to do
No routine action is needed. Review lipid response if high-dose supplements are used long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Quercetin?
MediHelp rates the interaction as minor. Atorvastatin and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin affects P-glycoprotein and CYP enzymes in vitro, but the effect on atorvastatin in humans is unclear. Any change in exposure is probably small.
How serious is the interaction between Atorvastatin and Quercetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Review lipid response if high-dose supplements are used long term.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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