Drug interactions
Atorvastatin + Telmisartan
Severity: Minor
Atorvastatin and Telmisartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telmisartan has been reported to inhibit OATP1B1 in vitro, which could increase atorvastatin exposure. Clinically meaningful myopathy from this combination is not well established, and the two drugs are widely used together.
What this interaction means in plain words
Atorvastatin and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atorvastatin belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Possible inhibition of OATP1B1-mediated hepatic uptake of atorvastatin by telmisartan.
What to do
No dose change is usually needed; advise patients to report unexplained muscle pain or weakness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Telmisartan?
MediHelp rates the interaction as minor. Atorvastatin and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Telmisartan has been reported to inhibit OATP1B1 in vitro, which could increase atorvastatin exposure. Clinically meaningful myopathy from this combination is not well established, and the two drugs are widely used together.
How serious is the interaction between Atorvastatin and Telmisartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; advise patients to report unexplained muscle pain or weakness.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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