Drug interactions
Atropine iv / + Fesoterodine
Severity: Moderate
Atropine iv / and Fesoterodine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Parenteral atropine combined with fesoterodine produces additive antimuscarinic effects such as tachycardia, urinary retention, dry mouth and confusion.
What this interaction means in plain words
Atropine iv / and Fesoterodine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Monitor heart rate, urinary output and mental status when atropine is given, and hold fesoterodine if significant anticholinergic toxicity develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fesoterodine
Frequently asked questions
Can I take Atropine iv / with Fesoterodine?
MediHelp rates the interaction as moderate. Atropine iv / and Fesoterodine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Parenteral atropine combined with fesoterodine produces additive antimuscarinic effects such as tachycardia, urinary retention, dry mouth and confusion.
How serious is the interaction between Atropine iv / and Fesoterodine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, urinary output and mental status when atropine is given, and hold fesoterodine if significant anticholinergic toxicity develops.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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