Drug interactions
azathioprine + febuxostat
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Severe/fatal myelosuppression; contraindicated.
Mechanism of action
XO inhibition.
Clinical management
Contraindicated.
Drug reference
References
Frequently asked questions
Can I take azathioprine with febuxostat?
The interaction is rated: Contraindicated. Severe/fatal myelosuppression; contraindicated.
How serious is the interaction between azathioprine and febuxostat?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between azathioprine and febuxostat managed?
Contraindicated.
Why do azathioprine and febuxostat interact?
XO inhibition.
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