Drug interactions
Azficel-t + Ibuprofen
Severity: Moderate
Azficel-t and Ibuprofen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is given by intradermal injection after a skin biopsy, and NSAIDs impair platelet function. Taking ibuprofen around the time of biopsy or injections may increase bruising and bleeding at those sites.
What this interaction means in plain words
Azficel-t and Ibuprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Ibuprofen inhibits platelet cyclooxygenase-1, reversibly reducing platelet aggregation and increasing procedural bleeding and bruising.
What to do
Avoid NSAIDs for a period before and after the biopsy and injection sessions as directed by the product labeling. Use paracetamol (acetaminophen) for analgesia instead.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ibuprofen
- Ibuprofen + Ketorolac Contraindicated
- Ibuprofen + Ketorolac intranasal Contraindicated
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
- Apixaban + Ibuprofen Major
Frequently asked questions
Can I take Azficel-t with Ibuprofen?
MediHelp rates the interaction as moderate. Azficel-t and Ibuprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is given by intradermal injection after a skin biopsy, and NSAIDs impair platelet function. Taking ibuprofen around the time of biopsy or injections may increase bruising and bleeding at those sites.
How serious is the interaction between Azficel-t and Ibuprofen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid NSAIDs for a period before and after the biopsy and injection sessions as directed by the product labeling. Use paracetamol (acetaminophen) for analgesia instead.
What other medicines interact with Ibuprofen?
MediHelp also lists interactions of Ibuprofen with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Ibuprofen page.
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