Drug interactions
Azficel-t + Tolmetin
Severity: Moderate
Azficel-t and Tolmetin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs can increase bruising or bleeding at the biopsy and injection sites used for azficel-T. The product labeling advises against concomitant NSAID use around these procedures.
What this interaction means in plain words
Azficel-t and Tolmetin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
NSAID-induced platelet dysfunction increases bleeding at procedure sites.
What to do
Avoid tolmetin around the time of biopsy and injections, stopping it ahead of procedures per the product labeling. Use an alternative analgesic such as paracetamol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Azficel-t with Tolmetin?
MediHelp rates the interaction as moderate. Azficel-t and Tolmetin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs can increase bruising or bleeding at the biopsy and injection sites used for azficel-T. The product labeling advises against concomitant NSAID use around these procedures.
How serious is the interaction between Azficel-t and Tolmetin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid tolmetin around the time of biopsy and injections, stopping it ahead of procedures per the product labeling. Use an alternative analgesic such as paracetamol.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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