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Drug interactions

Basiliximab + Cholera vaccine

Severity: Moderate

Basiliximab and Cholera vaccine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Basiliximab blocks T-cell activation and may weaken the response to vaccines. A live attenuated cholera vaccine could also pose a theoretical infection risk in an immunosuppressed patient.

What this interaction means in plain words

Basiliximab and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

IL-2 receptor blockade suppresses T-cell activation, reducing vaccine immunogenicity.

What to do

Give needed vaccines before transplantation when possible and avoid live vaccines during immunosuppression. Reassess immunity if the patient travels to endemic areas.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Basiliximab with Cholera vaccine?

MediHelp rates the interaction as moderate. Basiliximab and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab blocks T-cell activation and may weaken the response to vaccines. A live attenuated cholera vaccine could also pose a theoretical infection risk in an immunosuppressed patient.

How serious is the interaction between Basiliximab and Cholera vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give needed vaccines before transplantation when possible and avoid live vaccines during immunosuppression. Reassess immunity if the patient travels to endemic areas.

What other medicines interact with Basiliximab?

MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.

Full monographs, dosing and an interaction checker in the MediHelp app

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