Drug interactions
Basiliximab + Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine
Severity: Moderate
Basiliximab and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab may reduce the antibody response to this inactivated combination vaccine. There is no risk of vaccine-strain infection, but protection may be inadequate.
What this interaction means in plain words
Basiliximab and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
IL-2 receptor blockade reduces T-cell-dependent antibody responses.
What to do
Complete vaccination before transplant where possible; otherwise give as scheduled and check antibody levels if protection is critical.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Basiliximab and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine?
MediHelp rates the interaction as moderate. Basiliximab and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab may reduce the antibody response to this inactivated combination vaccine. There is no risk of vaccine-strain infection, but protection may be inadequate.
How serious is the interaction between Basiliximab and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete vaccination before transplant where possible; otherwise give as scheduled and check antibody levels if protection is critical.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
