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Drug interactions

Basiliximab + Haemophilus influenzae type b vaccine

Severity: Minor

Basiliximab and Haemophilus influenzae type b vaccine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Basiliximab may reduce the antibody response to the Hib conjugate vaccine. Protection may be suboptimal in transplant recipients vaccinated during therapy.

What this interaction means in plain words

Basiliximab and Haemophilus influenzae type b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

IL-2 receptor blockade suppresses T-cell help required for the antibody response.

What to do

Vaccinate before transplant where possible, otherwise consider revaccination or checking antibody response once immunosuppression is reduced.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Basiliximab with Haemophilus influenzae type b vaccine?

MediHelp rates the interaction as minor. Basiliximab and Haemophilus influenzae type b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Basiliximab may reduce the antibody response to the Hib conjugate vaccine. Protection may be suboptimal in transplant recipients vaccinated during therapy.

How serious is the interaction between Basiliximab and Haemophilus influenzae type b vaccine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before transplant where possible, otherwise consider revaccination or checking antibody response once immunosuppression is reduced.

What other medicines interact with Basiliximab?

MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.

Full monographs, dosing and an interaction checker in the MediHelp app

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