Drug interactions
Basiliximab + Hepatitis a / b vaccine
Severity: Moderate
Basiliximab and Hepatitis a / b vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab may reduce seroconversion after inactivated hepatitis vaccines. Transplant recipients often respond poorly anyway.
What this interaction means in plain words
Basiliximab and Hepatitis a / b vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
IL-2 receptor blockade impairs T-helper-dependent B-cell antibody production.
What to do
Vaccinate before transplant if possible; after transplant check anti-HBs and anti-HAV titers and revaccinate or boost if inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Hepatitis a / b vaccine?
MediHelp rates the interaction as moderate. Basiliximab and Hepatitis a / b vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab may reduce seroconversion after inactivated hepatitis vaccines. Transplant recipients often respond poorly anyway.
How serious is the interaction between Basiliximab and Hepatitis a / b vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before transplant if possible; after transplant check anti-HBs and anti-HAV titers and revaccinate or boost if inadequate.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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