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Drug interactions

Basiliximab + Influenza virus vaccine quadrivalent adjuvanted

Severity: Moderate

Basiliximab and Influenza virus vaccine quadrivalent adjuvanted: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Basiliximab may reduce the antibody response to inactivated influenza vaccine, leaving patients less protected. The vaccine remains safe and is still recommended for transplant recipients.

What this interaction means in plain words

Basiliximab and Influenza virus vaccine quadrivalent adjuvanted can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

T-cell suppression reduces the immune response to vaccine antigens.

What to do

Give the influenza vaccine as scheduled, ideally before or well after induction therapy, and rely on household immunization and early antiviral treatment if influenza occurs.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Basiliximab with Influenza virus vaccine quadrivalent adjuvanted?

MediHelp rates the interaction as moderate. Basiliximab and Influenza virus vaccine quadrivalent adjuvanted can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab may reduce the antibody response to inactivated influenza vaccine, leaving patients less protected. The vaccine remains safe and is still recommended for transplant recipients.

How serious is the interaction between Basiliximab and Influenza virus vaccine quadrivalent adjuvanted?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the influenza vaccine as scheduled, ideally before or well after induction therapy, and rely on household immunization and early antiviral treatment if influenza occurs.

What other medicines interact with Basiliximab?

MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.

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