Drug interactions
Basiliximab + Influenza virus vaccine quadrivalent
Severity: Moderate
Basiliximab and Influenza virus vaccine quadrivalent: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inactivated influenza vaccine remains recommended for transplant recipients, though basiliximab may lower the antibody response. The vaccine is not unsafe in this setting.
What this interaction means in plain words
Basiliximab and Influenza virus vaccine quadrivalent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
IL-2 receptor blockade reduces T-cell-dependent antibody responses.
What to do
Give the inactivated vaccine annually as indicated; consider timing away from the induction period and use of household vaccination.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Influenza virus vaccine quadrivalent?
MediHelp rates the interaction as moderate. Basiliximab and Influenza virus vaccine quadrivalent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Inactivated influenza vaccine remains recommended for transplant recipients, though basiliximab may lower the antibody response. The vaccine is not unsafe in this setting.
How serious is the interaction between Basiliximab and Influenza virus vaccine quadrivalent?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the inactivated vaccine annually as indicated; consider timing away from the induction period and use of household vaccination.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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