Drug interactions
Basiliximab + Mycophenolate
Severity: Moderate
Basiliximab and Mycophenolate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab is commonly given with mycophenolate, ciclosporin and corticosteroids as part of standard transplant immunosuppression. The combination adds to overall immunosuppression and infection risk but is an intended regimen rather than one to avoid.
What this interaction means in plain words
Basiliximab and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive immunosuppression via IL-2 receptor blockade and inhibition of lymphocyte purine synthesis.
What to do
Use within established transplant protocols and monitor for infection, leukopenia and gastrointestinal effects. Provide appropriate antimicrobial prophylaxis.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Mycophenolate?
MediHelp rates the interaction as moderate. Basiliximab and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab is commonly given with mycophenolate, ciclosporin and corticosteroids as part of standard transplant immunosuppression. The combination adds to overall immunosuppression and infection risk but is an intended regimen rather than one to avoid.
How serious is the interaction between Basiliximab and Mycophenolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use within established transplant protocols and monitor for infection, leukopenia and gastrointestinal effects. Provide appropriate antimicrobial prophylaxis.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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