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Drug interactions

Basiliximab + Poliovirus vaccine inactivated

Severity: Minor

Basiliximab and Poliovirus vaccine inactivated: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Basiliximab may reduce the antibody response to inactivated poliovirus vaccine. The vaccine is not live, so the concern is reduced protection rather than infection.

What this interaction means in plain words

Basiliximab and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

IL-2 receptor blockade suppresses T-cell help required for the antibody response.

What to do

Vaccinate before transplant when feasible, otherwise consider revaccination or checking antibody response once immunosuppression is reduced.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Basiliximab with Poliovirus vaccine inactivated?

MediHelp rates the interaction as minor. Basiliximab and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Basiliximab may reduce the antibody response to inactivated poliovirus vaccine. The vaccine is not live, so the concern is reduced protection rather than infection.

How serious is the interaction between Basiliximab and Poliovirus vaccine inactivated?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before transplant when feasible, otherwise consider revaccination or checking antibody response once immunosuppression is reduced.

What other medicines interact with Basiliximab?

MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.

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