Drug interactions
Basiliximab + Zoster vaccine live
Severity: Contraindicated
Basiliximab and Zoster vaccine live: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Live zoster vaccine given during basiliximab therapy may cause disseminated vaccine-strain varicella zoster infection. Immune response to the vaccine may also be inadequate.
What this interaction means in plain words
Basiliximab and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
Immunosuppression allows replication of live attenuated virus.
What to do
Do not give live zoster vaccine; use the recombinant non-live zoster vaccine if vaccination is indicated.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Zoster vaccine live?
MediHelp rates the interaction as contraindicated. Basiliximab and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live zoster vaccine given during basiliximab therapy may cause disseminated vaccine-strain varicella zoster infection. Immune response to the vaccine may also be inadequate.
How serious is the interaction between Basiliximab and Zoster vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live zoster vaccine; use the recombinant non-live zoster vaccine if vaccination is indicated.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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