Drug interactions
Bazedoxifene / conjugated estrogens + Ropinirole
Severity: Minor
Bazedoxifene / conjugated estrogens and Ropinirole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Estrogens inhibit CYP1A2 and have been reported to reduce ropinirole clearance, which may raise ropinirole levels. The effect is typically modest.
What this interaction means in plain words
Bazedoxifene / conjugated estrogens and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Estrogens inhibit CYP1A2-mediated metabolism of ropinirole.
What to do
Adjust ropinirole dose according to response when estrogen therapy is started or stopped. Watch for somnolence and dizziness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ropinirole
- Amisulpride + Ropinirole Contraindicated
- Chlorpromazine + Ropinirole Major
- Droperidol + Ropinirole Major
- Fluphenazine + Ropinirole Major
- Fluvoxamine + Ropinirole Major
- Haloperidol + Ropinirole Major
Frequently asked questions
Can I take Bazedoxifene / conjugated estrogens with Ropinirole?
MediHelp rates the interaction as minor. Bazedoxifene / conjugated estrogens and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Estrogens inhibit CYP1A2 and have been reported to reduce ropinirole clearance, which may raise ropinirole levels. The effect is typically modest.
How serious is the interaction between Bazedoxifene / conjugated estrogens and Ropinirole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Adjust ropinirole dose according to response when estrogen therapy is started or stopped. Watch for somnolence and dizziness.
What other medicines interact with Ropinirole?
MediHelp also lists interactions of Ropinirole with, for example, Amisulpride, Chlorpromazine, Droperidol. The full list is on the Ropinirole page.
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