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Drug interactions

Bcg vaccine live + Beclomethasone

Severity: Minor

Bcg vaccine live and Beclomethasone: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

High-dose or systemic corticosteroids can blunt vaccine response and increase the risk of disseminated infection from live vaccines. Standard-dose inhaled beclomethasone has low systemic exposure, so the risk is small.

What this interaction means in plain words

Bcg vaccine live and Beclomethasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Corticosteroid immunosuppression may impair immune response to live vaccine, though inhaled exposure is low.

What to do

Vaccination is generally acceptable with standard inhaled doses; for high doses or additional systemic steroids, defer the live vaccine according to local guidance.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bcg vaccine live with Beclomethasone?

MediHelp rates the interaction as minor. Bcg vaccine live and Beclomethasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose or systemic corticosteroids can blunt vaccine response and increase the risk of disseminated infection from live vaccines. Standard-dose inhaled beclomethasone has low systemic exposure, so the risk is small.

How serious is the interaction between Bcg vaccine live and Beclomethasone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccination is generally acceptable with standard inhaled doses; for high doses or additional systemic steroids, defer the live vaccine according to local guidance.

What other medicines interact with Beclomethasone?

MediHelp also lists interactions of Beclomethasone with, for example, Corticorelin, Macimorelin, Sipuleucel-t. The full list is on the Beclomethasone page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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