Drug interactions
Bcg vaccine live + Dexamethasone-neomycin-polymyxin
Severity: Minor
Bcg vaccine live and Dexamethasone-neomycin-polymyxin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids can impair the response to live vaccines and increase the risk of vaccine-strain infection. With ophthalmic or topical use, systemic exposure is minimal, so the risk is low.
What this interaction means in plain words
Bcg vaccine live and Dexamethasone-neomycin-polymyxin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Immunosuppression from systemic corticosteroids may reduce control of live vaccine organisms, but systemic exposure here is minimal.
What to do
No change is needed for standard ophthalmic or topical use. If extensive topical or prolonged use occurs, consider delaying BCG.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone-neomycin-polymyxin
- Dexamethasone-neomycin-polymyxin + Ketorolac Major
- Dexamethasone-neomycin-polymyxin + Lapatinib Major
- Dexamethasone-neomycin-polymyxin + Levofloxacin Major
- Dexamethasone-neomycin-polymyxin + Mifepristone Major
- Dexamethasone-neomycin-polymyxin + Moxifloxacin Major
- Aldesleukin + Dexamethasone-neomycin-polymyxin Moderate
Frequently asked questions
Can I take Bcg vaccine live with Dexamethasone-neomycin-polymyxin?
MediHelp rates the interaction as minor. Bcg vaccine live and Dexamethasone-neomycin-polymyxin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids can impair the response to live vaccines and increase the risk of vaccine-strain infection. With ophthalmic or topical use, systemic exposure is minimal, so the risk is low.
How serious is the interaction between Bcg vaccine live and Dexamethasone-neomycin-polymyxin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is needed for standard ophthalmic or topical use. If extensive topical or prolonged use occurs, consider delaying BCG.
What other medicines interact with Dexamethasone-neomycin-polymyxin?
MediHelp also lists interactions of Dexamethasone-neomycin-polymyxin with, for example, Ketorolac, Lapatinib, Levofloxacin. The full list is on the Dexamethasone-neomycin-polymyxin page.
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