Drug interactions
Beclomethasone inhaled + Hydrochlorothiazide-valsartan
Severity: Minor
Beclomethasone inhaled and Hydrochlorothiazide-valsartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids promote renal potassium loss, and high-dose inhaled beclomethasone may add to the hypokalemia caused by hydrochlorothiazide. Systemic exposure from usual inhaled doses is low, so the clinical effect is generally small.
What this interaction means in plain words
Beclomethasone inhaled and Hydrochlorothiazide-valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mild mineralocorticoid-related potassium wasting from systemically absorbed corticosteroid adds to thiazide-induced kaliuresis.
What to do
Monitor serum potassium periodically if high inhaled doses are used or other potassium-lowering drugs are co-prescribed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-valsartan
- Aliskiren + Hydrochlorothiazide-valsartan Contraindicated
- Dofetilide + Hydrochlorothiazide-valsartan Contraindicated
- Hydrochlorothiazide-valsartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-valsartan Major
- Amifostine + Hydrochlorothiazide-valsartan Major
- Amiloride + Hydrochlorothiazide-valsartan Major
Frequently asked questions
Can I take Beclomethasone inhaled with Hydrochlorothiazide-valsartan?
MediHelp rates the interaction as minor. Beclomethasone inhaled and Hydrochlorothiazide-valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids promote renal potassium loss, and high-dose inhaled beclomethasone may add to the hypokalemia caused by hydrochlorothiazide. Systemic exposure from usual inhaled doses is low, so the clinical effect is generally small.
How serious is the interaction between Beclomethasone inhaled and Hydrochlorothiazide-valsartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium periodically if high inhaled doses are used or other potassium-lowering drugs are co-prescribed.
What other medicines interact with Hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-valsartan page.
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