Drug interactions
Belladonna and opium + Brimonidine
Severity: Minor
Belladonna and opium and Brimonidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Opium contributes opioid CNS and respiratory depression, and brimonidine may add to sedation. The effect is likely small with ophthalmic brimonidine.
What this interaction means in plain words
Belladonna and opium and Brimonidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depression.
What to do
Monitor for excess drowsiness and warn patients about driving. Use the lowest effective opioid dose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Brimonidine
- Brimonidine + Isocarboxazid Contraindicated
- Brimonidine + Linezolid Contraindicated
- Brimonidine + Phenelzine Contraindicated
- Brimonidine + Procarbazine Contraindicated
- Brimonidine + Rasagiline Contraindicated
- Brimonidine + Selegiline Contraindicated
Frequently asked questions
Can I take Belladonna and opium with Brimonidine?
MediHelp rates the interaction as minor. Belladonna and opium and Brimonidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Opium contributes opioid CNS and respiratory depression, and brimonidine may add to sedation. The effect is likely small with ophthalmic brimonidine.
How serious is the interaction between Belladonna and opium and Brimonidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excess drowsiness and warn patients about driving. Use the lowest effective opioid dose.
What other medicines interact with Brimonidine?
MediHelp also lists interactions of Brimonidine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Brimonidine page.
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