Drug interactions
Bemiparin + Quinine
Severity: Moderate
Bemiparin and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine can rarely cause thrombocytopenia and has been linked to hemorrhagic complications, which may add to the bleeding tendency of a low-molecular-weight heparin. The pharmacokinetic and direct anticoagulant interaction is not well established.
What this interaction means in plain words
Bemiparin and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
No established pharmacokinetic mechanism; possible additive bleeding risk through quinine-induced thrombocytopenia.
What to do
Monitor platelet counts and watch for bleeding signs during co-use. Stop quinine and reassess anticoagulation if platelets fall significantly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Bemiparin with Quinine?
MediHelp rates the interaction as moderate. Bemiparin and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine can rarely cause thrombocytopenia and has been linked to hemorrhagic complications, which may add to the bleeding tendency of a low-molecular-weight heparin. The pharmacokinetic and direct anticoagulant interaction is not well established.
How serious is the interaction between Bemiparin and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor platelet counts and watch for bleeding signs during co-use. Stop quinine and reassess anticoagulation if platelets fall significantly.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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