Drug interactions
Bendroflumethiazide + Candesartan
Severity: Minor
Bendroflumethiazide and Candesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination gives additive blood pressure lowering and is widely used. The ARB offsets thiazide-induced potassium loss, though hypotension, volume depletion and renal function changes can occur.
What this interaction means in plain words
Bendroflumethiazide and Candesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effect; ARB reduces aldosterone-mediated potassium loss caused by the thiazide.
What to do
Monitor blood pressure, electrolytes and renal function after initiation or dose changes, particularly in the elderly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Bendroflumethiazide and Candesartan, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Candesartan
- Aliskiren + Candesartan Contraindicated
- Candesartan + Sparsentan Contraindicated
- Amifostine + Candesartan Major
- Amiloride + Candesartan Major
- Amlodipine-benazepril + Candesartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Candesartan Major
Frequently asked questions
Can I take Bendroflumethiazide with Candesartan?
MediHelp rates the interaction as minor. Bendroflumethiazide and Candesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The combination gives additive blood pressure lowering and is widely used. The ARB offsets thiazide-induced potassium loss, though hypotension, volume depletion and renal function changes can occur.
How serious is the interaction between Bendroflumethiazide and Candesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, electrolytes and renal function after initiation or dose changes, particularly in the elderly.
What other medicines interact with Candesartan?
MediHelp also lists interactions of Candesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Candesartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
