Drug interactions
Benperidol + Fesoterodine
Severity: Moderate
Benperidol and Fesoterodine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benperidol has some anticholinergic activity, so combined use with fesoterodine can add to dry mouth, constipation, urinary retention and confusion. Slowed gut motility may also affect absorption of oral antipsychotic.
What this interaction means in plain words
Benperidol and Fesoterodine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for anticholinergic toxicity and cognitive changes, especially in older adults, and adjust doses if symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fesoterodine
Frequently asked questions
Can I take Benperidol with Fesoterodine?
MediHelp rates the interaction as moderate. Benperidol and Fesoterodine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Benperidol has some anticholinergic activity, so combined use with fesoterodine can add to dry mouth, constipation, urinary retention and confusion. Slowed gut motility may also affect absorption of oral antipsychotic.
How serious is the interaction between Benperidol and Fesoterodine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity and cognitive changes, especially in older adults, and adjust doses if symptoms occur.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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