Drug interactions
Benzphetamine + Glipizide-metformin
Severity: Minor
Benzphetamine and Glipizide-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benzphetamine, a sympathomimetic anorectic, may change glucose requirements, and weight loss can lower the dose needed of antidiabetic drugs. Hypoglycemia may occur as the combination is withdrawn or with weight loss.
What this interaction means in plain words
Benzphetamine and Glipizide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Sympathomimetic effects and weight loss alter insulin sensitivity and glucose requirements.
What to do
Monitor blood glucose when starting or stopping benzphetamine and adjust antidiabetic doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glipizide-metformin
Frequently asked questions
Can I take Benzphetamine with Glipizide-metformin?
MediHelp rates the interaction as minor. Benzphetamine and Glipizide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Benzphetamine, a sympathomimetic anorectic, may change glucose requirements, and weight loss can lower the dose needed of antidiabetic drugs. Hypoglycemia may occur as the combination is withdrawn or with weight loss.
How serious is the interaction between Benzphetamine and Glipizide-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping benzphetamine and adjust antidiabetic doses.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
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