Drug interactions
Berotralstat + Budesonide
Severity: Minor
Berotralstat and Budesonide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Berotralstat inhibits P-glycoprotein and may modestly increase budesonide exposure. The effect is expected to be small and relevant mainly with prolonged or high-dose budesonide.
What this interaction means in plain words
Berotralstat and Budesonide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Berotralstat belongs to Miscellaneous; Budesonide belongs to Respiratory.
Why it happens
Inhibition of P-glycoprotein efflux, increasing budesonide absorption and reducing clearance.
What to do
No routine adjustment is needed. Monitor for corticosteroid adverse effects if long-term high-dose budesonide is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Berotralstat
- Berotralstat + Ergotamine Major
- Berotralstat + Nilotinib Major
- Berotralstat + Pimozide Major
- Berotralstat + Quinidine Major
- Berotralstat + Quinine Major
- Berotralstat + Tacrolimus Major
Frequently asked questions
Can I take Berotralstat with Budesonide?
MediHelp rates the interaction as minor. Berotralstat and Budesonide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Berotralstat inhibits P-glycoprotein and may modestly increase budesonide exposure. The effect is expected to be small and relevant mainly with prolonged or high-dose budesonide.
How serious is the interaction between Berotralstat and Budesonide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor for corticosteroid adverse effects if long-term high-dose budesonide is used.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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