Drug interactions
Betaxolol + Hydralazine
Severity: Minor
Betaxolol and Hydralazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Together they lower blood pressure more than either alone. Beta-blockers also help blunt the reflex tachycardia caused by hydralazine, so the combination is often used intentionally, but excess hypotension can occur.
What this interaction means in plain words
Betaxolol and Hydralazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Hydralazine belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering from arterial vasodilation and beta-1 blockade.
What to do
Monitor blood pressure and heart rate during initiation and titration. Adjust doses if symptomatic hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Other interactions of Hydralazine
- Amifostine + Hydralazine Major
- Aceclofenac + Hydralazine Moderate
- Acemetacin + Hydralazine Moderate
- Aldesleukin + Hydralazine Moderate
- Avanafil + Hydralazine Moderate
- Benzphetamine + Hydralazine Moderate
Frequently asked questions
Can I take Betaxolol with Hydralazine?
MediHelp rates the interaction as minor. Betaxolol and Hydralazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Together they lower blood pressure more than either alone. Beta-blockers also help blunt the reflex tachycardia caused by hydralazine, so the combination is often used intentionally, but excess hypotension can occur.
How serious is the interaction between Betaxolol and Hydralazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during initiation and titration. Adjust doses if symptomatic hypotension develops.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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