Drug interactions
Betaxolol + Nifedipine
Severity: Moderate
Betaxolol and Nifedipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol and nifedipine are often combined, and beta-blockade can offset the reflex tachycardia from nifedipine. Excessive hypotension or, in patients with impaired ventricular function, heart failure can occasionally occur.
What this interaction means in plain words
Betaxolol and Nifedipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Nifedipine belongs to Cardiovascular.
Why it happens
Additive vasodilatory and negative inotropic or chronotropic pharmacodynamic effects.
What to do
Monitor blood pressure and heart rate during initiation and dose changes, and use caution in patients with heart failure.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Betaxolol and Nifedipine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Other interactions of Nifedipine
Frequently asked questions
Can I take Betaxolol with Nifedipine?
MediHelp rates the interaction as moderate. Betaxolol and Nifedipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Betaxolol and nifedipine are often combined, and beta-blockade can offset the reflex tachycardia from nifedipine. Excessive hypotension or, in patients with impaired ventricular function, heart failure can occasionally occur.
How serious is the interaction between Betaxolol and Nifedipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during initiation and dose changes, and use caution in patients with heart failure.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
