Drug interactions
Betaxolol + Sacubitril-valsartan
Severity: Minor
Betaxolol and Sacubitril-valsartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol and sacubitril/valsartan together can lower blood pressure and heart rate more than either alone. This combination is often used intentionally in heart failure but can cause dizziness or hypotension.
What this interaction means in plain words
Betaxolol and Sacubitril-valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Sacubitril-valsartan belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering through beta-blockade and angiotensin receptor and neprilysin inhibition.
What to do
Monitor blood pressure and heart rate when starting or titrating either drug. Adjust doses if symptomatic hypotension or bradycardia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Betaxolol and Sacubitril-valsartan, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Sacubitril-valsartan
- Aliskiren + Sacubitril-valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Captopril + Sacubitril-valsartan Contraindicated
- Enalapril + Sacubitril-valsartan Contraindicated
- Fosinopril + Sacubitril-valsartan Contraindicated
- Lisinopril + Sacubitril-valsartan Contraindicated
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Sacubitril-valsartan?
MediHelp rates the interaction as minor. Betaxolol and Sacubitril-valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Betaxolol and sacubitril/valsartan together can lower blood pressure and heart rate more than either alone. This combination is often used intentionally in heart failure but can cause dizziness or hypotension.
How serious is the interaction between Betaxolol and Sacubitril-valsartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or titrating either drug. Adjust doses if symptomatic hypotension or bradycardia occurs.
What other medicines interact with Sacubitril-valsartan?
MediHelp also lists interactions of Sacubitril-valsartan with, for example, Aliskiren, Benazepril, Captopril. The full list is on the Sacubitril-valsartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
