Drug interactions
Betaxolol + Timolol
Severity: Moderate
Betaxolol and Timolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol is a beta-blocker, and systemic timolol, including absorption from eye drops, adds to its effect. Together they can cause bradycardia, hypotension, and AV conduction disturbances.
What this interaction means in plain words
Betaxolol and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Timolol belongs to Cardiovascular.
Why it happens
Additive beta-adrenergic receptor blockade.
What to do
Avoid duplicate oral beta-blockade. If timolol eye drops are needed, monitor heart rate and blood pressure, or choose a non-beta-blocker glaucoma agent in patients with bradycardia or heart block.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Frequently asked questions
Can I take Betaxolol with Timolol?
MediHelp rates the interaction as moderate. Betaxolol and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Betaxolol is a beta-blocker, and systemic timolol, including absorption from eye drops, adds to its effect. Together they can cause bradycardia, hypotension, and AV conduction disturbances.
How serious is the interaction between Betaxolol and Timolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid duplicate oral beta-blockade. If timolol eye drops are needed, monitor heart rate and blood pressure, or choose a non-beta-blocker glaucoma agent in patients with bradycardia or heart block.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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